Octant and BMS present "Deep Mutational Scan of TYK2 Reveals Protein-Drug Interactions” at Stanford Drug Discovery Symposium 2024

April 30, 2024

Study will evaluate the safety, tolerability and pharmacokinetics (PK) of OCT-980 in healthy volunteers

Initiation of the study marks Octant’s transition to a clinical-stage company

Deep Mutational Scan of TYK2 Reveals Protein-Drug Interactions and Novel Therapeutic Sites of Action

Conor J. Howard, Nathan S. Abell, Robert Warneford-Thomson, Eden Mahdavi, Carmen Resnick, Alan Su, Nabil Mohammed, Erin M. Thompson, Emily Holzinger, Katrina Catalano, Stephen C.Wilson, Joseph C. Maranville, Payal R. Sheth, Robert M. Plenge, Sriram Kosuri, Diane E. Dickel

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